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Prophylactic Application of CpG Oligonucleotides Augments the Early Host Response and Confers Protection in Acute Melioidosis

Prophylactic administration of CpG oligodeoxynucleotides (CpG ODNs) is known to confer protection against lethal sepsis caused by Burkholderia pseudomallei in the mouse model. The mechanisms whereby CpG regulates the innate immune response to provide protection against B. pseudomallei, however, are...

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Detalles Bibliográficos
Autores principales: Judy, Barbara M., Taylor, Katherine, Deeraksa, Arpaporn, Johnston, R. Katie, Endsley, Janice J., Vijayakumar, Sudhamathi, Aronson, Judith F., Estes, D. Mark, Torres, Alfredo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309019/
https://www.ncbi.nlm.nih.gov/pubmed/22448290
http://dx.doi.org/10.1371/journal.pone.0034176