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Prophylactic Application of CpG Oligonucleotides Augments the Early Host Response and Confers Protection in Acute Melioidosis
Prophylactic administration of CpG oligodeoxynucleotides (CpG ODNs) is known to confer protection against lethal sepsis caused by Burkholderia pseudomallei in the mouse model. The mechanisms whereby CpG regulates the innate immune response to provide protection against B. pseudomallei, however, are...
Autores principales: | Judy, Barbara M., Taylor, Katherine, Deeraksa, Arpaporn, Johnston, R. Katie, Endsley, Janice J., Vijayakumar, Sudhamathi, Aronson, Judith F., Estes, D. Mark, Torres, Alfredo G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309019/ https://www.ncbi.nlm.nih.gov/pubmed/22448290 http://dx.doi.org/10.1371/journal.pone.0034176 |
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