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Use of differential scanning fluorimetry as a high-throughput assay to identify nuclear receptor ligands
Identification of ligands that interact with nuclear receptors is both a major biological problem and an important initial step in drug discovery. Several in vitro and in vivo techniques are commonly used to screen ligand candidates against nuclear receptors; however, none of the current assays allo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Nuclear Receptor Signaling Atlas
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309076/ https://www.ncbi.nlm.nih.gov/pubmed/22438792 http://dx.doi.org/10.1621/nrs.10002 |