NF-κB-mediated degradation of the co-activator RIP140 regulates inflammatory response and contributes to endotoxin tolerance

Endotoxin tolerance (ET) triggered by prior exposure to Toll-like receptor (TLR) ligands provides a mechanism to dampen inflammatory cytokines. Receptor-interacting protein 140 (RIP140) interacts with NF-κB to regulate the expression of proinflammatory cytokine genes. We identify lipopolysaccharide...

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Detalles Bibliográficos
Autores principales: Ho, Ping-Chih, Tsui, Yao-Chen, Feng, Xudong, Greaves, David R., Wei, Li-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309172/
https://www.ncbi.nlm.nih.gov/pubmed/22388040
http://dx.doi.org/10.1038/ni.2238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309172/
https://www.ncbi.nlm.nih.gov/pubmed/22388040
http://dx.doi.org/10.1038/ni.2238

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