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Effects of 4-week administration of simvastatin in different doses on heart rate and blood pressure after metoprolol injection in normocholesterolaemic and normotensive rats

INTRODUCTION: Statins and β1-adrenergic antagonists are well established in cardiovascular events therapy and prevention. The previous study showed that statins might impact on β-adrenergic signalling and blood pressure in a dose-dependent manner. The aim of the study was to evaluate the impact of 4...

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Detalles Bibliográficos
Autores principales: Owczarek, Jacek, Jasińska, Magdalena, Wejman, Irena, Kurczewska, Urszula, Orszulak-Michalak, Daria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309431/
https://www.ncbi.nlm.nih.gov/pubmed/22457669
http://dx.doi.org/10.5114/aoms.2012.27275