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Age-related BMAL1 change affects mouse bone marrow stromal cell proliferation and osteo-differentiation potential

INTRODUCTION: Aging people's bone regeneration potential is always impaired. Bone marrow stromal cells (MSCs) contain progenitors of osteoblasts. Donor age may affect MSCs’ proliferation and differentiation potential, but the genomic base is still unknown. Due to recent research's indicati...

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Detalles Bibliográficos
Autores principales: Chen, Yijia, Xu, Xiaomei, Tan, Zhen, Ye, Cui, Zhao, Qing, Chen, Yangxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309433/
https://www.ncbi.nlm.nih.gov/pubmed/22457671
http://dx.doi.org/10.5114/aoms.2012.27277