Enriched environment treatment reverses depression-like behavior and restores reduced hippocampal neurogenesis and protein levels of brain-derived neurotrophic factor in mice lacking its expression through promoter IV

Promoter IV-driven expression of brain-derived neurotrophic factor (BDNF), a major neuronal growth factor, is implicated in the pathophysiology of major depression. We previously reported that mice lacking expression of BDNF through promoter IV (BDNF-KIV mice) exhibit a depression-like phenotype. He...

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Detalles Bibliográficos
Autores principales: Jha, S, Dong, B, Sakata, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309483/
https://www.ncbi.nlm.nih.gov/pubmed/22832656
http://dx.doi.org/10.1038/tp.2011.33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309483/
https://www.ncbi.nlm.nih.gov/pubmed/22832656
http://dx.doi.org/10.1038/tp.2011.33

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