Metabolite profiling of antidepressant drug action reveals novel drug targets beyond monoamine elevation

Currently used antidepressants elevate monoamine levels in the synaptic cleft. There is good reason to assume that this is not the only source for antidepressant therapeutic activities and that secondary downstream effects may be relevant for alleviating symptoms of depression. We attempted to eluci...

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Detalles Bibliográficos
Autores principales: Webhofer, C, Gormanns, P, Tolstikov, V, Zieglgänsberger, W, Sillaber, I, Holsboer, F, Turck, C W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309495/
https://www.ncbi.nlm.nih.gov/pubmed/22832350
http://dx.doi.org/10.1038/tp.2011.56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309495/
https://www.ncbi.nlm.nih.gov/pubmed/22832350
http://dx.doi.org/10.1038/tp.2011.56

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