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Metabolite profiling of antidepressant drug action reveals novel drug targets beyond monoamine elevation
Currently used antidepressants elevate monoamine levels in the synaptic cleft. There is good reason to assume that this is not the only source for antidepressant therapeutic activities and that secondary downstream effects may be relevant for alleviating symptoms of depression. We attempted to eluci...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309495/ https://www.ncbi.nlm.nih.gov/pubmed/22832350 http://dx.doi.org/10.1038/tp.2011.56 |