Increased methylation of glucocorticoid receptor gene (NR3C1) in adults with a history of childhood maltreatment: a link with the severity and type of trauma

Childhood maltreatment, through epigenetic modification of the glucocorticoid receptor gene (NR3C1), influences the hypothalamic–pituitary–adrenal axis (HPA axis). We investigated whether childhood maltreatment and its severity were associated with increased methylation of the exon 1(F) NR3C1 promot...

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Detalles Bibliográficos
Autores principales: Perroud, N, Paoloni-Giacobino, A, Prada, P, Olié, E, Salzmann, A, Nicastro, R, Guillaume, S, Mouthon, D, Stouder, C, Dieben, K, Huguelet, P, Courtet, P, Malafosse, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309499/
https://www.ncbi.nlm.nih.gov/pubmed/22832351
http://dx.doi.org/10.1038/tp.2011.60

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309499/
https://www.ncbi.nlm.nih.gov/pubmed/22832351
http://dx.doi.org/10.1038/tp.2011.60

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