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Increased de novo copy number variants in the offspring of older males

The offspring of older fathers have an increased risk of neurodevelopmental disorders, such as schizophrenia and autism. In light of the evidence implicating copy number variants (CNVs) with schizophrenia and autism, we used a mouse model to explore the hypothesis that the offspring of older males h...

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Detalles Bibliográficos
Autores principales: Flatscher-Bader, T, Foldi, C J, Chong, S, Whitelaw, E, Moser, R J, Burne, T H J, Eyles, D W, McGrath, J J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309504/
https://www.ncbi.nlm.nih.gov/pubmed/22832608
http://dx.doi.org/10.1038/tp.2011.30