Schizophrenia risk gene CAV1 is both pro-psychotic and required for atypical antipsychotic drug actions in vivo

Caveolin-1 (Cav-1) is a scaffolding protein important for regulating receptor signaling cascades by partitioning signaling molecules into membrane microdomains. Disruption of the CAV1 gene has recently been identified as a rare structural variant associated with schizophrenia. Although Cav-1 knockou...

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Detalles Bibliográficos
Autores principales: Allen, J A, Yadav, P N, Setola, V, Farrell, M, Roth, B L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309505/
https://www.ncbi.nlm.nih.gov/pubmed/22832607
http://dx.doi.org/10.1038/tp.2011.35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309505/
https://www.ncbi.nlm.nih.gov/pubmed/22832607
http://dx.doi.org/10.1038/tp.2011.35

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