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Interactions of human truncated DISC1 proteins: implications for schizophrenia

Numerous genetic linkage and association reports have implicated the Disrupted-in-Schizophrenia (DISC1) gene in psychiatric illness. The Scottish family translocation, predicted to encode a C-terminus-truncated protein, suggests involvement of short isoforms in the pathophysiology of mental disorder...

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Detalles Bibliográficos
Autores principales: Newburn, E N, Hyde, T M, Ye, T, Morita, Y, Weinberger, D R, Kleinman, J E, Lipska, B K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309510/
https://www.ncbi.nlm.nih.gov/pubmed/22832604
http://dx.doi.org/10.1038/tp.2011.31