Tetrahydrohyperforin prevents cognitive deficit, Aβ deposition, tau phosphorylation and synaptotoxicity in the APPswe/PSEN1ΔE9 model of Alzheimer's disease: a possible effect on APP processing

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a progressive deterioration of cognitive abilities, amyloid-β peptide (Aβ) accumulation and synaptic alterations. Previous studies indicated that hyperforin, a component of the St John's Wort, prevents Aβ neurotoxici...

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Detalles Bibliográficos
Autores principales: Inestrosa, N C, Tapia-Rojas, C, Griffith, T N, Carvajal, F J, Benito, M J, Rivera-Dictter, A, Alvarez, A R, Serrano, F G, Hancke, J L, Burgos, P V, Parodi, J, Varela-Nallar, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309512/
https://www.ncbi.nlm.nih.gov/pubmed/22832522
http://dx.doi.org/10.1038/tp.2011.19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309512/
https://www.ncbi.nlm.nih.gov/pubmed/22832522
http://dx.doi.org/10.1038/tp.2011.19

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