Serotonin 1A receptor-mediated signaling through ERK and PKCα is essential for normal synaptogenesis in neonatal mouse hippocampus

Aberrant expression of the presynaptic serotonin 1A receptor (5-HT(1A)-R) because of a polymorphism in the 5-HT(1A)-R gene is associated with severe depression in human, whereas its absence up to postnatal day 21 (P21) in the forebrain of mice results in heightened anxiety in adulthood. These observ...

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Detalles Bibliográficos
Autores principales: Mogha, A, Guariglia, S R, Debata, P R, Wen, G Y, Banerjee, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309541/
https://www.ncbi.nlm.nih.gov/pubmed/22832728
http://dx.doi.org/10.1038/tp.2011.58

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309541/
https://www.ncbi.nlm.nih.gov/pubmed/22832728
http://dx.doi.org/10.1038/tp.2011.58

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