Joint Rare Variant Association Test of the Average and Individual Effects for Sequencing Studies

For many complex traits, single nucleotide polymorphisms (SNPs) identified from genome-wide association studies (GWAS) only explain a small percentage of heritability. Next generation sequencing technology makes it possible to explore unexplained heritability by identifying rare variants (RVs). Exis...

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Detalles Bibliográficos
Autores principales: Wang, Yuanjia, Chen, Yin-Hsiu, Yang, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309869/
https://www.ncbi.nlm.nih.gov/pubmed/22468164
http://dx.doi.org/10.1371/journal.pone.0032485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309869/
https://www.ncbi.nlm.nih.gov/pubmed/22468164
http://dx.doi.org/10.1371/journal.pone.0032485

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