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Joint Rare Variant Association Test of the Average and Individual Effects for Sequencing Studies
For many complex traits, single nucleotide polymorphisms (SNPs) identified from genome-wide association studies (GWAS) only explain a small percentage of heritability. Next generation sequencing technology makes it possible to explore unexplained heritability by identifying rare variants (RVs). Exis...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309869/ https://www.ncbi.nlm.nih.gov/pubmed/22468164 http://dx.doi.org/10.1371/journal.pone.0032485 |