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The adaptor protein p62/SQSTM1 in osteoclast signaling pathways

Paget's disease of bone (PDB) is a skeletal disorder characterized by focal and disorganized increases in bone turnover and overactive osteoclasts. The discovery of mutations in the SQSTM1/p62 gene in numerous patients has identified protein p62 as an important modulator of bone turnover. In bo...

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Detalles Bibliográficos
Autores principales: McManus, Stephen, Roux, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309942/
https://www.ncbi.nlm.nih.gov/pubmed/22216904
http://dx.doi.org/10.1186/1750-2187-7-1