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The adaptor protein p62/SQSTM1 in osteoclast signaling pathways
Paget's disease of bone (PDB) is a skeletal disorder characterized by focal and disorganized increases in bone turnover and overactive osteoclasts. The discovery of mutations in the SQSTM1/p62 gene in numerous patients has identified protein p62 as an important modulator of bone turnover. In bo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309942/ https://www.ncbi.nlm.nih.gov/pubmed/22216904 http://dx.doi.org/10.1186/1750-2187-7-1 |