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NOD/scid IL-2Rg(null )mice: a preclinical model system to evaluate human dendritic cell-based vaccine strategies in vivo

BACKGROUND: To date very few systems have been described for preclinical investigations of human cellular therapeutics in vivo. However, the ability to carry out comparisons of new cellular vaccines in vivo would be of substantial interest for design of clinical studies. Here we describe a humanized...

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Detalles Bibliográficos
Autores principales: Spranger, Stefani, Frankenberger, Bernhard, Schendel, Dolores J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309948/
https://www.ncbi.nlm.nih.gov/pubmed/22364226
http://dx.doi.org/10.1186/1479-5876-10-30