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Fine mapping of a linkage peak with integration of lipid traits identifies novel coronary artery disease genes on chromosome 5

BACKGROUND: Coronary artery disease (CAD), and one of its intermediate risk factors, dyslipidemia, possess a demonstrable genetic component, although the genetic architecture is incompletely defined. We previously reported a linkage peak on chromosome 5q31-33 for early-onset CAD where the strength o...

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Detalles Bibliográficos
Autores principales: Nolan, Daniel K, Sutton, Beth, Haynes, Carol, Johnson, Jessica, Sebek, Jacqueline, Dowdy, Elaine, Crosslin, David, Crossman, David, Sketch, Michael H, Granger, Christopher B, Seo, David, Goldschmidt-Clermont, Pascal, Kraus, William E, Gregory, Simon G, Hauser, Elizabeth R, Shah, Svati H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309961/
https://www.ncbi.nlm.nih.gov/pubmed/22369142
http://dx.doi.org/10.1186/1471-2156-13-12