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A Common SMAD7 Variant Is Associated with Risk of Colorectal Cancer: Evidence from a Case-Control Study and a Meta-Analysis

BACKGROUND: A common genetic variant, rs4939827, located in SMAD7, was identified by two recent genome-wide association (GWA) studies to be strongly associated with the risk of colorectal cancer (CRC). However, the following replication studies yielded conflicting results. METHOD AND FINDINGS: We co...

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Detalles Bibliográficos
Autores principales: Song, Qibin, Zhu, Beibei, Hu, Weiguo, Cheng, Liming, Gong, Hongyun, Xu, Bin, Zheng, Xiawen, Zou, Li, Zhong, Rong, Duan, Shengyu, Chen, Wei, Rui, Rui, Wu, Jing, Miao, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310071/
https://www.ncbi.nlm.nih.gov/pubmed/22457752
http://dx.doi.org/10.1371/journal.pone.0033318