Cargando…

Two-photon scanning microscopy of in vivo sensory responses of cortical neurons genetically encoded with a fluorescent voltage sensor in rat

A fluorescent voltage sensor protein “Flare” was created from a Kv1.4 potassium channel with YFP situated to report voltage-induced conformational changes in vivo. The RNA virus Sindbis introduced Flare into neurons in the binocular region of visual cortex in rat. Injection sites were selected based...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahrens, Kurt F., Heider, Barbara, Lee, Hanson, Isacoff, Ehud Y., Siegel, Ralph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310150/
https://www.ncbi.nlm.nih.gov/pubmed/22461770
http://dx.doi.org/10.3389/fncir.2012.00015