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Two-photon scanning microscopy of in vivo sensory responses of cortical neurons genetically encoded with a fluorescent voltage sensor in rat
A fluorescent voltage sensor protein “Flare” was created from a Kv1.4 potassium channel with YFP situated to report voltage-induced conformational changes in vivo. The RNA virus Sindbis introduced Flare into neurons in the binocular region of visual cortex in rat. Injection sites were selected based...
Autores principales: | Ahrens, Kurt F., Heider, Barbara, Lee, Hanson, Isacoff, Ehud Y., Siegel, Ralph M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310150/ https://www.ncbi.nlm.nih.gov/pubmed/22461770 http://dx.doi.org/10.3389/fncir.2012.00015 |
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