The Synergistic Effect of Valsartan and LAF237 [(S)-1-[(3-Hydroxy-1-Adamantyl)Ammo]acetyl-2-Cyanopyrrolidine] on Vascular Oxidative Stress and Inflammation in Type 2 Diabetic Mice

Aim. To investigate the combination effects and mechanisms of valsartan (angiotensin II type 1 receptor blocker) and LAF237 (DPP-IV inhibitor) on prevention against oxidative stress and inflammation injury in db/db mice aorta. Methods. Db/db mice (n = 40) were randomized to receive valsartan, LAF237...

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Detalles Bibliográficos
Autores principales: Shen, Min, Sun, Dongdong, Li, Weijie, Liu, Bing, Wang, Shenxu, Zhang, Zheng, Cao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310178/
https://www.ncbi.nlm.nih.gov/pubmed/22474415
http://dx.doi.org/10.1155/2012/146194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310178/
https://www.ncbi.nlm.nih.gov/pubmed/22474415
http://dx.doi.org/10.1155/2012/146194

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