Corresponding Functional Dynamics across the Hsp90 Chaperone Family: Insights from a Multiscale Analysis of MD Simulations

Understanding how local protein modifications, such as binding small-molecule ligands, can trigger and regulate large-scale motions of large protein domains is a major open issue in molecular biology. We address various aspects of this problem by analyzing and comparing atomistic simulations of Hsp9...

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Detalles Bibliográficos
Autores principales: Morra, Giulia, Potestio, Raffaello, Micheletti, Cristian, Colombo, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310708/
https://www.ncbi.nlm.nih.gov/pubmed/22457611
http://dx.doi.org/10.1371/journal.pcbi.1002433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310708/
https://www.ncbi.nlm.nih.gov/pubmed/22457611
http://dx.doi.org/10.1371/journal.pcbi.1002433

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