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Physiological Notch Signaling Maintains Bone Homeostasis via RBPjk and Hey Upstream of NFATc1

Notch signaling between neighboring cells controls many cell fate decisions in metazoans both during embryogenesis and in postnatal life. Previously, we uncovered a critical role for physiological Notch signaling in suppressing osteoblast differentiation in vivo. However, the contribution of individ...

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Detalles Bibliográficos
Autores principales: Tu, Xiaolin, Chen, Jianquan, Lim, Joohyun, Karner, Courtney M., Lee, Seung-Yon, Heisig, Julia, Wiese, Cornelia, Surendran, Kameswaran, Kopan, Raphael, Gessler, Manfred, Long, Fanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310726/
https://www.ncbi.nlm.nih.gov/pubmed/22457635
http://dx.doi.org/10.1371/journal.pgen.1002577