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Evidence for Positive Selection on a Number of MicroRNA Regulatory Interactions during Recent Human Evolution

MicroRNA (miRNA)–mediated gene regulation is of critical functional importance in animals and is thought to be largely constrained during evolution. However, little is known regarding evolutionary changes of the miRNA network and their role in human evolution. Here we show that a number of miRNA bin...

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Detalles Bibliográficos
Autores principales: Li, Jingjing, Liu, Yu, Xin, Xiaofeng, Kim, Taehyung Simon, Cabeza, Eduardo Aguiar, Ren, Jie, Nielsen, Rasmus, Wrana, Jeffrey L., Zhang, Zhaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310733/
https://www.ncbi.nlm.nih.gov/pubmed/22457636
http://dx.doi.org/10.1371/journal.pgen.1002578