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Widespread Site-Dependent Buffering of Human Regulatory Polymorphism
The average individual is expected to harbor thousands of variants within non-coding genomic regions involved in gene regulation. However, it is currently not possible to interpret reliably the functional consequences of genetic variation within any given transcription factor recognition sequence. T...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310774/ https://www.ncbi.nlm.nih.gov/pubmed/22457641 http://dx.doi.org/10.1371/journal.pgen.1002599 |