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A Single Nucleotide Polymorphism in Tetherin Promotes Retrovirus Restriction In Vivo
Tetherin is a membrane protein of unusual topology expressed from rodents to humans that accumulates enveloped virus particles on the surface of infected cells. However, whether this ‘tethering’ activity promotes or restricts retroviral spread during acute retrovirus infection in vivo is controversi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310811/ https://www.ncbi.nlm.nih.gov/pubmed/22457621 http://dx.doi.org/10.1371/journal.ppat.1002596 |