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Liver X Receptors Regulate the Transcriptional Activity of the Glucocorticoid Receptor: Implications for the Carbohydrate Metabolism

GLUCOCORTICOIDS are steroid hormones that strongly influence intermediary carbohydrate metabolism by increasing the transcription rate of glucose-6-phosphatase (G6Pase), a key enzyme of gluconeogenesis, and suppress the immune system through the glucocorticoid receptor (GR). The liver X receptors (L...

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Detalles Bibliográficos
Autores principales: Nader, Nancy, Ng, Sinnie Sin Man, Wang, Yonghong, Abel, Brent S., Chrousos, George P., Kino, Tomoshige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310817/
https://www.ncbi.nlm.nih.gov/pubmed/22457708
http://dx.doi.org/10.1371/journal.pone.0026751