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Thriving under Stress: Selective Translation of HIV-1 Structural Protein mRNA during Vpr-Mediated Impairment of eIF4E Translation Activity

Translation is a regulated process and is pivotal to proper cell growth and homeostasis. All retroviruses rely on the host translational machinery for viral protein synthesis and thus may be susceptible to its perturbation in response to stress, co-infection, and/or cell cycle arrest. HIV-1 infectio...

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Detalles Bibliográficos
Autores principales: Sharma, Amit, Yilmaz, Alper, Marsh, Kim, Cochrane, Alan, Boris-Lawrie, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310836/
https://www.ncbi.nlm.nih.gov/pubmed/22457629
http://dx.doi.org/10.1371/journal.ppat.1002612