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MRP14 (S100A9) Protein Interacts with Alzheimer Beta-Amyloid Peptide and Induces Its Fibrillization

Increasing evidence supports the contribution of local inflammation to the development of Alzheimer's disease (AD) pathology, although the precise mechanisms are not clear. In this study, we demonstrate that the pro-inflammatory protein S100A9 interacts with the A[Image: see text]1–40 peptide a...

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Detalles Bibliográficos
Autores principales: Zhang, Ce, Liu, Yonggang, Gilthorpe, Jonathan, van der Maarel, Johan R. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310843/
https://www.ncbi.nlm.nih.gov/pubmed/22457725
http://dx.doi.org/10.1371/journal.pone.0032953