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Targeting Gene-Viro-Therapy with AFP driving Apoptin gene shows potent antitumor effect in hepatocarcinoma

BACKGROUND: Gene therapy and viral therapy are used for cancer therapy for many years, but the results are less than satisfactory. Our aim was to construct a new recombinant adenovirus which is more efficient to kill hepatocarcinoma cells but more safe to normal cells. METHODS: By using the Cancer T...

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Detalles Bibliográficos
Autores principales: Zhang, Kang-Jian, Qian, Jing, Wang, Shi-Bing, Yang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311074/
https://www.ncbi.nlm.nih.gov/pubmed/22321574
http://dx.doi.org/10.1186/1423-0127-19-20