X-Chromosome Inactivation in Rett Syndrome Human Induced Pluripotent Stem Cells

Rett syndrome (RTT) is a neurodevelopmental disorder that affects girls due primarily to heterozygous mutations in the X-linked gene encoding methyl-CpG binding protein 2 (MECP2). Random X-chromosome inactivation (XCI) results in cellular mosaicism in which some cells express wild-type (WT) MECP2 wh...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheung, Aaron Y. L., Horvath, Lindsay M., Carrel, Laura, Ellis, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311266/
https://www.ncbi.nlm.nih.gov/pubmed/22470355
http://dx.doi.org/10.3389/fpsyt.2012.00024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311266/
https://www.ncbi.nlm.nih.gov/pubmed/22470355
http://dx.doi.org/10.3389/fpsyt.2012.00024

Ejemplares similares