Cargando…

X-Chromosome Inactivation in Rett Syndrome Human Induced Pluripotent Stem Cells

Rett syndrome (RTT) is a neurodevelopmental disorder that affects girls due primarily to heterozygous mutations in the X-linked gene encoding methyl-CpG binding protein 2 (MECP2). Random X-chromosome inactivation (XCI) results in cellular mosaicism in which some cells express wild-type (WT) MECP2 wh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheung, Aaron Y. L., Horvath, Lindsay M., Carrel, Laura, Ellis, James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Psychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311266/ https://www.ncbi.nlm.nih.gov/pubmed/22470355 http://dx.doi.org/10.3389/fpsyt.2012.00024

Ejemplares similares

Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation
por: Cheung, Aaron Y.L., et al.
Publicado: (2011)

X chromosome inactivation does not necessarily determine the severity of the phenotype in Rett syndrome patients
por: Xiol, Clara, et al.
Publicado: (2019)

Rett Syndrome: Genes, Synapses, Circuits, and Therapeutics
por: Banerjee, Abhishek, et al.
Publicado: (2012)

Deletion of an X-Inactivation Boundary Disrupts Adjacent Gene Silencing
por: Horvath, Lindsay M., et al.
Publicado: (2013)

Rett syndrome induced pluripotent stem cell-derived neurons reveal novel neurophysiological alterations
por: Farra, N, et al.
Publicado: (2012)

Analysis of X‐inactivation status in a Rett syndrome natural history study cohort
por: Fang, Xiaolan, et al.
Publicado: (2022)

Human induced pluripotent stem cells from two azoospermic patients with Klinefelter syndrome show similar X chromosome inactivation behavior to female pluripotent stem cells
por: Panula, Sarita, et al.
Publicado: (2019)

Single-cell analyses of X Chromosome inactivation dynamics and pluripotency during differentiation
por: Chen, Geng, et al.
Publicado: (2016)

Modeling Rett Syndrome with Human Pluripotent Stem Cells: Mechanistic Outcomes and Future Clinical Perspectives
por: Gomes, Ana Rita, et al.
Publicado: (2021)

Preventing erosion of X-chromosome inactivation in human embryonic stem cells
por: Cloutier, Marissa, et al.
Publicado: (2022)

Random X chromosome inactivation in patients with Klinefelter syndrome
por: Kinjo, Kenichi, et al.
Publicado: (2020)

Inferring genes that escape X-Chromosome inactivation reveals important contribution of variable escape genes to sex-biased diseases
por: Sauteraud, Renan, et al.
Publicado: (2021)

MECP2 Isoform-Specific Vectors with Regulated Expression for Rett Syndrome Gene Therapy
por: Rastegar, Mojgan, et al.
Publicado: (2009)

Attrition of X Chromosome Inactivation in Aged Hematopoietic Stem Cells
por: Grigoryan, Ani, et al.
Publicado: (2021)

Rett syndrome
por: Sitholey, Prabhat, et al.
Publicado: (2005)

Automatic vocalisation-based detection of fragile X syndrome and Rett syndrome
por: Pokorny, Florian B., et al.
Publicado: (2022)

Exit from Naive Pluripotency Induces a Transient X Chromosome Inactivation-like State in Males
por: Sousa, Elsa J., et al.
Publicado: (2018)

Characterisation of X chromosome status of human extended pluripotent stem cells
por: Wang, Ying, et al.
Publicado: (2023)

Detection of skewed X-chromosome inactivation in Fragile X syndrome and X chromosome aneuploidy using quantitative melt analysis
por: Godler, David E., et al.
Publicado: (2015)

Complexities of X chromosome inactivation status in female human induced pluripotent stem cells—a brief review and scientific update for autism research
por: Dandulakis, Mary G., et al.
Publicado: (2016)

Uniparental disomy of the entire X chromosome in Turner syndrome patient-specific induced pluripotent stem cells
por: Luo, Yumei, et al.
Publicado: (2015)

A transcriptomic signature of X chromosome overdosage in Saudi Klinefelter syndrome induced pluripotent stem cells
por: Astro, Veronica, et al.
Publicado: (2023)

Selection of X-chromosome Inactivation Model
por: Wang, Jian, et al.
Publicado: (2017)

Polycomb complexes in X chromosome inactivation
por: Brockdorff, Neil
Publicado: (2017)

Mechanisms of Choice in X-Chromosome Inactivation
por: Furlan, Giulia, et al.
Publicado: (2022)

X-Chromosome Inactivation and Related Diseases
por: Sun, Zhuo, et al.
Publicado: (2022)

Rett Syndrome and Fragile X Syndrome: Different Etiology With Common Molecular Dysfunctions
por: Bach, Snow, et al.
Publicado: (2021)

Normal histone modifications on the inactive X chromosome in ICF and Rett syndrome cells: implications for methyl-CpG binding proteins
por: Gartler, Stanley M, et al.
Publicado: (2004)

Mechanics and Dynamics of X-Chromosome Pairing at X Inactivation
por: Scialdone, Antonio, et al.
Publicado: (2008)

Stable X Chromosome Reactivation in Female Human Induced Pluripotent Stem Cells
por: Barakat, Tahsin Stefan, et al.
Publicado: (2015)

Late Replication of the Inactive X Chromosome Is Independent of the Compactness of Chromosome Territory in Human Pluripotent Stem Cells
por: Panova, A. V., et al.
Publicado: (2013)

X‐chromosomal inactivation patterns in women with Fabry disease
por: Wagenhäuser, Laura, et al.
Publicado: (2022)

Mitochondrial Proteome Changes in Rett Syndrome
por: Golubiani, Gocha, et al.
Publicado: (2023)

Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome
por: Machiela, Mitchell J., et al.
Publicado: (2016)

X Chromosome Inactivation during Drosophila Spermatogenesis
por: Hense, Winfried, et al.
Publicado: (2007)

X-chromosome inactivation: the molecular basis of silencing
por: Panning, Barbara
Publicado: (2008)

The Evolutionary Pathway of X Chromosome Inactivation in Mammals
por: Shevchenko, A.I., et al.
Publicado: (2013)

X Chromosome Inactivation in Opioid Addicted Women
por: Vousooghi, Nasim, et al.
Publicado: (2015)

X Chromosome Inactivation during Grasshopper Spermatogenesis
por: Viera, Alberto, et al.
Publicado: (2021)

Molecular Signatures of Response to Mecasermin in Children With Rett Syndrome
por: Shovlin, Stephen, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_iekjp3akta66jqmaher5c6tv23