Low-Dose Cd Induces Hepatic Gene Hypermethylation, along with the Persistent Reduction of Cell Death and Increase of Cell Proliferation in Rats and Mice

BACKGROUND: Cadmium (Cd) is classified as a human carcinogen probably associated with epigenetic changes. DNA methylation is one of epigenetic mechanisms by which cells control gene expression. Therefore, the present study genome-widely screened the methylation-altered genes in the liver of rats pre...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Li, Yang, Tan, Yi, Miao, Xiao, Liu, Xu-Dong, Shao, Chen, Yang, Xiao-Hui, Turdi, Subat, Ma, Li-Jie, Ren, Jun, Cai, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311546/
https://www.ncbi.nlm.nih.gov/pubmed/22457795
http://dx.doi.org/10.1371/journal.pone.0033853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311546/
https://www.ncbi.nlm.nih.gov/pubmed/22457795
http://dx.doi.org/10.1371/journal.pone.0033853

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