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Carbon Monoxide Induced Erythroid Differentiation of K562 Cells Mimics the Central Macrophage Milieu in Erythroblastic Islands

Growing evidence supports the role of erythroblastic islands (EI) as microenvironmental niches within bone marrow (BM), where cell-cell attachments are suggested as crucial for erythroid maturation. The inducible form of the enzyme heme oxygenase, HO-1, which conducts heme degradation, is absent in...

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Detalles Bibliográficos
Autores principales: Toobiak, Shlomi, Shaklai, Mati, Shaklai, Nurith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311552/
https://www.ncbi.nlm.nih.gov/pubmed/22457802
http://dx.doi.org/10.1371/journal.pone.0033940