Suppression of Adiponectin by Aberrantly Glycosylated IgA1 in Glomerular Mesangial Cells In Vitro and In Vivo

The pathogenesis of IgA nephropathy (IgAN) may be associated with the mesangial deposition of aberrantly glycosylated IgA1. To identify mediators affected by aberrantly glycosylated IgA1 in cultured human mesangial cells (HMCs), we generated enzymatically modified desialylated and degalactosylated (...

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Detalles Bibliográficos
Autores principales: Inoue, Tatsuyuki, Sugiyama, Hitoshi, Kitagawa, Masashi, Takiue, Keiichi, Morinaga, Hiroshi, Ogawa, Ayu, Kikumoto, Yoko, Kitamura, Shinji, Maeshima, Yohei, Makino, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311555/
https://www.ncbi.nlm.nih.gov/pubmed/22457806
http://dx.doi.org/10.1371/journal.pone.0033965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311555/
https://www.ncbi.nlm.nih.gov/pubmed/22457806
http://dx.doi.org/10.1371/journal.pone.0033965

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