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Rapamycin inhibition of baculovirus recombinant (BVr) ribosomal protein S6 kinase (S6K1) is mediated by an event other than phosphorylation

BACKGROUND: Ribosomal protein S6 kinase 1(S6K1) is an evolutionary conserved kinase that is activated in response to growth factors and viral stimuli to influence cellular growth and proliferation. This downstream effector of target of rapamycin (TOR) signaling cascade is known to be directly activa...

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Detalles Bibliográficos
Autores principales: Beigh, Mushtaq A, Showkat, Mehvish, ul Hussain, Mahboob, Latoo, Shafat A, Majeed, Sheikh T, Andrabi, Khurshid I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311567/
https://www.ncbi.nlm.nih.gov/pubmed/22376175
http://dx.doi.org/10.1186/1478-811X-10-4