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Prostate Cancer Risk Is not Altered by TP53AIP1 Germline Mutations in a German Case-Control Series

Prostate cancer susceptibility has previously been associated with truncating germline variants in the gene TP53AIP1 (tumor protein p53 regulated apoptosis inducing protein 1). For two apparently recurrent mutations (p.Q22fs and p.S32X) a remarkable OR of 5.1 was reported for prostate cancer risk. S...

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Detalles Bibliográficos
Autores principales: Luedeke, Manuel, Coinac, Irina, Linnert, Carmen M., Bogdanova, Natalia, Rinckleb, Antje E., Schrader, Mark, Vogel, Walther, Hoegel, Josef, Meyer, Andreas, Dörk, Thilo, Maier, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311578/
https://www.ncbi.nlm.nih.gov/pubmed/22457820
http://dx.doi.org/10.1371/journal.pone.0034128