Cargando…

Prostate Cancer Risk Is not Altered by TP53AIP1 Germline Mutations in a German Case-Control Series

Prostate cancer susceptibility has previously been associated with truncating germline variants in the gene TP53AIP1 (tumor protein p53 regulated apoptosis inducing protein 1). For two apparently recurrent mutations (p.Q22fs and p.S32X) a remarkable OR of 5.1 was reported for prostate cancer risk. S...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luedeke, Manuel, Coinac, Irina, Linnert, Carmen M., Bogdanova, Natalia, Rinckleb, Antje E., Schrader, Mark, Vogel, Walther, Hoegel, Josef, Meyer, Andreas, Dörk, Thilo, Maier, Christiane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311578/ https://www.ncbi.nlm.nih.gov/pubmed/22457820 http://dx.doi.org/10.1371/journal.pone.0034128

Ejemplares similares

Intronic TP53 Germline Sequence Variants Modify the Risk in German Breast/Ovarian Cancer Families
por: Liu, Xuan, et al.
Publicado: (2004)

Germline mutation in the TP53 gene in uveal melanoma
por: Hajkova, Nikola, et al.
Publicado: (2018)

Germline TP53 mutations in Finnish breast cancer patients
por: Rapakko, K, et al.
Publicado: (2000)

Number of rare germline CNVs and TP53 mutation types
por: Silva, Amanda G, et al.
Publicado: (2012)

Clinical implications of germline mutations in breast cancer: TP53
por: Schon, Katherine, et al.
Publicado: (2017)

Emerging insights into ethnic-specific TP53 germline variants
por: Fischer, Nicholas W, et al.
Publicado: (2023)

Germline TP53 mutational spectrum in French Canadians with breast cancer
por: Arcand, Suzanna L, et al.
Publicado: (2015)

Somatic TP53 variants frequently confound germline testing results
por: Weitzel, Jeffrey N., et al.
Publicado: (2017)

Germline TP53 Testing in Breast Cancers: Why, When and How?
por: Evans, D. Gareth, et al.
Publicado: (2020)

Choroid Plexus Carcinomas With TP53 Germline Mutations: Management and Outcome
por: Li, Yanong, et al.
Publicado: (2021)

Inherited and de novo germline TP53 mutations in adult-onset sarcoma
por: Thomas, David M, et al.
Publicado: (2012)

Inherited and de novo germline TP53 mutations in adult-onset sarcoma
por: Thomas, DM, et al.
Publicado: (2012)

Modeling the prevalent germline TP53 R337H mutation in mouse
por: Park, Ji-Hoon, et al.
Publicado: (2019)

Blood functional assay for rapid clinical interpretation of germline TP53 variants
por: Raad, Sabine, et al.
Publicado: (2021)

AIP gene germline variants in adult Polish patients with apparently sporadic pituitary macroadenomas
por: Trofimiuk-Müldner, Małgorzata, et al.
Publicado: (2023)

Novel AIP mutation in exon 6 causing acromegaly in a German family
por: Detomas, M., et al.
Publicado: (2023)

Whole-body MRI within a surveillance program for carriers with clinically actionable germline TP53 variants - the Swedish constitutional TP53 study SWEP53
por: Omran, Meis, et al.
Publicado: (2020)

Mutation analysis of the MDM4 gene in German breast cancer patients
por: Reincke, Scarlett, et al.
Publicado: (2008)

Germline TP53 Mutation and Clinical Characteristics of Korean Patients With Li-Fraumeni Syndrome
por: Park, Kyoung-Jin, et al.
Publicado: (2016)

Effects of MDM2, MDM4 and TP53 Codon 72 Polymorphisms on Cancer Risk in a Cohort Study of Carriers of TP53 Germline Mutations
por: Fang, Shenying, et al.
Publicado: (2010)

Analysis of the Li-Fraumeni Spectrum Based on an International Germline TP53 Variant Data Set: An International Agency for Research on Cancer TP53 Database Analysis
por: Kratz, Christian P., et al.
Publicado: (2021)

TOPBP1 missense variant Arg309Cys and breast cancer in a German hospital-based case-control study
por: Blaut, Magda A, et al.
Publicado: (2010)

A Mouse Homolog of a Human TP53 Germline Mutation Reveals a Lipolytic Activity of p53
por: Kang, Ju-Gyeong, et al.
Publicado: (2020)

Association of the germline TP53 R337H mutation with breast cancer in southern Brazil
por: Assumpção, Juliana G, et al.
Publicado: (2011)

Increased Oxidative Damage in Carriers of the Germline TP53 p.R337H Mutation
por: Macedo, Gabriel S., et al.
Publicado: (2012)

Association of the germline TP53 R337H mutation with breast cancer in southern Brazil
por: Assumpção, Juliana G, et al.
Publicado: (2008)

High Frequency of Germline TP53 Mutations in a Prospective Adult-Onset Sarcoma Cohort
por: Mitchell, Gillian, et al.
Publicado: (2013)

Clinical characteristics and registry-validated extended pedigrees of germline TP53 mutation carriers in Denmark
por: Stoltze, Ulrik, et al.
Publicado: (2018)

Mutation screening of germline TP53 mutations in high-risk Chinese breast cancer patients
por: Kwong, Ava, et al.
Publicado: (2020)

Clinical Features of Breast Cancer in South Korean Patients with Germline TP53 Gene Mutations
por: Alyami, Hassan, et al.
Publicado: (2021)

A novel germline mutation of TP53 with breast cancer diagnosed as Li–Fraumeni syndrome
por: Kai, Masaya, et al.
Publicado: (2022)

Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis
por: Light, Nicholas, et al.
Publicado: (2023)

Mitigating the Risk of t-MNs Development: TP53 or Not TP53?
por: Tesio, Melania
Publicado: (2023)

AIP Annual Meeting
por: Abashian, Alexander
Publicado: (1984)

AIP Annual Meeting
por: Margolis, Bernard, et al.
Publicado: (1980)

AIP Annual Meeting
por: Caswell, William E, et al.
Publicado: (1983)

AIP Annual Meeting
por: Heusch, Clemens A, et al.
Publicado: (1982)

AIP Annual Meeting
por: Carlson, Carl E
Publicado: (1975)

AIP Congress 2006
Publicado: (2006)

The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis
por: Leroy, Bernard, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_jf7ugf46tljmup2dnnfudjpf5l