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The Role of the Parkinson's Disease Gene PARK9 in Essential Cellular Pathways and the Manganese Homeostasis Network in Yeast

YPK9 (Yeast PARK9; also known as YOR291W) is a non-essential yeast gene predicted by sequence to encode a transmembrane P-type transport ATPase. However, its substrate specificity is unknown. Mutations in the human homolog of YPK9, ATP13A2/PARK9, have been linked to genetic forms of early onset park...

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Detalles Bibliográficos
Autores principales: Chesi, Alessandra, Kilaru, Austin, Fang, Xiaodong, Cooper, Antony A., Gitler, Aaron D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311584/
https://www.ncbi.nlm.nih.gov/pubmed/22457822
http://dx.doi.org/10.1371/journal.pone.0034178