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The Tumor Suppressive Role of eIF3f and Its Function in Translation Inhibition and rRNA Degradation

Deregulated translation plays an important role in human cancer. We previously reported decreased eukaryotic initiation factor 3 subunit f (eIF3f) expression in pancreatic cancer. Whether decreased eIF3f expression can transform normal epithelial cells is not known. In our current study, we found ev...

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Detalles Bibliográficos
Autores principales: Wen, Fushi, Zhou, Renyuan, Shen, Alex, Choi, Andrew, Uribe, Diana, Shi, Jiaqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311619/
https://www.ncbi.nlm.nih.gov/pubmed/22457825
http://dx.doi.org/10.1371/journal.pone.0034194