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Increased Gut Permeability and Microbiota Change Associate with Mesenteric Fat Inflammation and Metabolic Dysfunction in Diet-Induced Obese Mice

We investigated the relationship between gut health, visceral fat dysfunction and metabolic disorders in diet-induced obesity. C57BL/6J mice were fed control or high saturated fat diet (HFD). Circulating glucose, insulin and inflammatory markers were measured. Proximal colon barrier function was ass...

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Detalles Bibliográficos
Autores principales: Lam, Yan Y., Ha, Connie W. Y., Campbell, Craig R., Mitchell, Andrew J., Dinudom, Anuwat, Oscarsson, Jan, Cook, David I., Hunt, Nicholas H., Caterson, Ian D., Holmes, Andrew J., Storlien, Len H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311621/
https://www.ncbi.nlm.nih.gov/pubmed/22457829
http://dx.doi.org/10.1371/journal.pone.0034233