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Propionyl-L-carnitine Corrects Metabolic and Cardiovascular Alterations in Diet-Induced Obese Mice and Improves Liver Respiratory Chain Activity

AIMS: Obesity is a primary contributor to acquired insulin resistance leading to the development of type 2 diabetes and cardiovascular alterations. The carnitine derivate, propionyl-L-carnitine (PLC), plays a key role in energy control. Our aim was to evaluate metabolic and cardiovascular effects of...

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Detalles Bibliográficos
Autores principales: Mingorance, Carmen, Duluc, Lucie, Chalopin, Matthieu, Simard, Gilles, Ducluzeau, Pierre-Henri, Herrera, Maria Dolores, Alvarez de Sotomayor, Maria, Andriantsitohaina, Ramaroson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311627/
https://www.ncbi.nlm.nih.gov/pubmed/22457831
http://dx.doi.org/10.1371/journal.pone.0034268