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Activation Status of Wnt/ß-Catenin Signaling in Normal and Neoplastic Breast Tissues: Relationship to HER2/neu Expression in Human and Mouse

Wnt/ß-catenin signaling is strongly implicated in neoplasia, but the role of this pathway in human breast cancer has been controversial. Here, we examined Wnt/ß-catenin pathway activation as a function of breast cancer progression, and tested for a relationship with HER2/neu expression, using a huma...

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Detalles Bibliográficos
Autores principales: Khalil, Sara, Tan, Grace A., Giri, Dilip D., Zhou, Xi Kathy, Howe, Louise R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311643/
https://www.ncbi.nlm.nih.gov/pubmed/22457761
http://dx.doi.org/10.1371/journal.pone.0033421