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Computable Features Required to Evaluate the Efficacy of Drugs and a Universal Algorithm to Find Optimally Effective Drug in a Drug Complex
BACKGROUND: The H1N1 pandemic in 2009 and the H5N1 pandemic in 2005 demonstrated that the drugs approved to treat influenza A viruses have low efficacy. This provided a stimulus for new studies of influenza A viruses in the context of the methods used in drug design developed over the past 100 years...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311648/ https://www.ncbi.nlm.nih.gov/pubmed/22457784 http://dx.doi.org/10.1371/journal.pone.0033709 |