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Novel Chalcone-Based Fluorescent Human Histamine H(3) Receptor Ligands as Pharmacological Tools

Novel fluorescent chalcone-based ligands at human histamine H(3) receptors (hH(3)R) have been designed, synthesized, and characterized. Compounds described are non-imidazole analogs of ciproxifan with a tetralone motif. Tetralones as chemical precursors and related fluorescent chalcones exhibit affi...

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Detalles Bibliográficos
Autores principales: Tomasch, Miriam, Schwed, J. Stephan, Weizel, Lilia, Stark, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312100/
https://www.ncbi.nlm.nih.gov/pubmed/22470321
http://dx.doi.org/10.3389/fnsys.2012.00014