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Novel Chalcone-Based Fluorescent Human Histamine H(3) Receptor Ligands as Pharmacological Tools
Novel fluorescent chalcone-based ligands at human histamine H(3) receptors (hH(3)R) have been designed, synthesized, and characterized. Compounds described are non-imidazole analogs of ciproxifan with a tetralone motif. Tetralones as chemical precursors and related fluorescent chalcones exhibit affi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312100/ https://www.ncbi.nlm.nih.gov/pubmed/22470321 http://dx.doi.org/10.3389/fnsys.2012.00014 |