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Microarchitecture, but Not Bone Mechanical Properties, Is Rescued with Growth Hormone Treatment in a Mouse Model of Growth Hormone Deficiency

Growth hormone (GH) deficiency is related to an increased fracture risk although it is not clear if this is due to compromised bone quality or a small bone size. We investigated the relationship between bone macrostructure, microarchitecture and mechanical properties in a GH-deficient (GHD) mouse mo...

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Detalles Bibliográficos
Autores principales: Kristensen, Erika, Hallgrímsson, Benedikt, Morck, Douglas W., Boyd, Steven K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312192/
https://www.ncbi.nlm.nih.gov/pubmed/22505889
http://dx.doi.org/10.1155/2012/294965