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Heme Oxygenase-1 Induction and Organic Nitrate Therapy: Beneficial Effects on Endothelial Dysfunction, Nitrate Tolerance, and Vascular Oxidative Stress

Organic nitrates are a group of very effective anti-ischemic drugs. They are used for the treatment of patients with stable angina, acute myocardial infarction, and chronic congestive heart failure. A major therapeutic limitation inherent to organic nitrates is the development of tolerance, which oc...

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Detalles Bibliográficos
Autores principales: Daiber, Andreas, Oelze, Matthias, Wenzel, Philip, Bollmann, Franziska, Pautz, Andrea, Kleinert, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312327/
https://www.ncbi.nlm.nih.gov/pubmed/22506100
http://dx.doi.org/10.1155/2012/842632